Miscarriage Causes: Immune Mechanisms

The fetus contains foreign genetic material coming from the father, but in normal circumstances it does not get rejected. However, in some women the immune system may reject the fetus and cause a miscarriage either by being high in numbers or by abnormal hostile activity. There are several immune disorders:-

Antinuclear Antibodies

What are Antinuclear Antibodies?

Antinuclear Antibodies (ANA) are associated with several diseases such as Systemic Lupus Erythematosus (SLE).

The miscarriage rate in SLE patients is much higher than that of the general population. Although most women who suffer recurrent miscarriages do not have clinical signs of SLE, many exhibit autoimmune phenomena similar to that seen in SLE patients.

The placentas in these women are sometimes found to be inflamed and weakened.


If your results revealed that you have positive ANA, I will offer you treatment with Prednisolone.